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The Change of Salivary Flow Rate according to Olfactory Stimulation
J Oral Med Pain 2017;42:62-71
Published online September 30, 2017
© 2017 Korean Academy of Orofacial Pain and Oral Medicine

Hee Noh1, Yeong-Gwan Im2, Byung-Gook Kim1

1Department of Oral Medicine, School of Dentistry, Chonnam National University, Gwangju, Korea
2Department of Oral Medicine, Chonnam National University Dental Hospital, Gwangju, Korea
Correspondence to: Byung-Gook Kim
Department of Oral Medicine, School of Dentistry, Chonnam National University, 33 Yongbong-ro, Buk-gu, Gwangju 61186, Korea
Tel: +82-62-530-5574 Fax: +82-62-530-5679 E-mail:
Received February 8, 2017; Revised June 6, 2017; Accepted September 3, 2017.
This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Purpose: The purpose of this study was to examine the rate of salivation before and after olfactory stimulation using BPO (black pepper oil) and then, to collect basic data for screening the possibility of introducing olfactory stimulus to prevent and improve dry mouth.
Methods: The subjects in this study were 60 college students in Jeon-Nam province. The subjects were randomly divided into 3 groups; the BPO group (n=20), the lavender oil (LVO) group (n=20), and the distilled water (DW) group (n=20). The amount of whole saliva before and after olfactory stimulation was measured 14 times for a 4-week period.
Results: In the BPO and LVO groups, the amount of whole saliva increased after the olfactory stimulation and it was most prominent in the BPO group (p<0.05). The difference of whole salivation was higher in the BPO group (p<0.05) and there was no significant difference in the salivary flow rate in the DW group. After 14 times of measurement for 4 weeks, the BPO and LVO groups showed an increase in salivary rate at an early stage compared without stimulation (p<0.05), but there was no significant difference between the 2 groups in the middle. Since the twelfth measurement, whole saliva secretion increased and maintained the elevated level (p<0.05).
Conclusions: The olfactory stimulation using BPO may contribute to stimulating salivation. Further studies are needed for subjects with dry mouth symptoms. In the future, qualitative and quantitative studies should be conducted for people who complains about oral dryness.
Keywords : Salivation; Smell; Xerostomia

June 2018, 43 (2)