Fig. 1. (A) Clinical features of right ventral tongue at the first visit in 2012 showed whitish reticulation with erythema observed in the posterior part of tongue. (B) Histologic features of right ventral tongue in 2012 revealed a number of rete pegs and band like infiltration of lymphocytes. Epithelial dysplasia was also present (hematoxylin-eosin [H&E] stain: ×200). (C) Similar clinical features of whitish plaque with erythema were noted on the left ventral tongue in 2012. (D) Slightly thicker whitish plaque was observed on the left ventral tongue in 2017. (E) The histologic features from the whitish plaque on the left ventral tongue in 2017 showed well-differentiated squamous cell carcinoma cells invasion (black arrows) (H&E stain: ×200).
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